Our Mission

Who We Are

At NeuraCell, we are committed to engaging in life changing research. Do you want a team of dedicated scientists with years of experience to conduct your contract research? Do you value high quality data generated with integrity and scientific rigor? You’ve come to the right place!

We are a not-for-profit core facility that engages in contract research, production of high quality cell lines, and other services. Our group has over 20 years of experience working with various stem cells, including induced pluripotent stem cells (iPSCs), neural progenitor cells (NPCs), Schwann cells, adult retinal pigment epithelial cells (RPE), and everything you need to grow them. We produce forebrain and midbrain organoids, which are the emerging platforms for 3D tissue modeling. Our research covers tau pathology modeling for neurodegenerative diseases. In addition to cells, organoids, and media, we also provide a range of molecular tools including custom lentiviral shRNA and over-expression vectors, single cell sequencing, flow cytometry-fluorescence-activated cell sorting (FACS), and drug screening assays. Contact us for consultation on characterization services to assess how your products or reagents affect stem cell performance and behavior. Give us a call today, we would love to hear from you!

Our Team

Steven Lotz – Director

Taylor Bertucci PhD – Research Scientist

Sue Borden – Research Technician

Katherine Stevens – Research Technician

Jack Huber – Research Technician

Additional Scientific Team

NeuraCell is backed by a team of scientists at Neural Stem Cell Institute, a not-for-profit organization, led by the Scientific Director, Dr. Sally Temple, an expert in the field of stem cell research and recipient of numerous recognition awards in the field.

ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids (PubMed)

Bowles K, Silva MC, Whitney K, Bertucci T, Berlind J, Lai J, Garza J, Boles N, Mahali S, Strang K, Marsh J, Chen C, Pugh D, Liu Y, Gordon R, Goderie S, Chowdhury R, Lotz S, Lane K, Crary J, Haggarty S, Karch K, Ichida J, Goate A, Temple S. Cell PMID: 34314701. 2021.

Sustained levels of FGF2 maintain undifferentiated stem cell cultures with biweekly feeding (PubMed)

Lotz S, Goderie S, Tokas N, Hirsch SE, Ahmad F, Corneo B, Le S, Banerjee A, Kane RS, Stern JH, Temple S, Fasano CA. PLoS One. 2013;8(2):e56289. doi: 10.1371/journal.pone.0056289. Epub 2013 Feb 20. PMID: 23437109; PMCID: PMC3577833.

Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol (PubMed)

Glasauer S, Goderie S, Rauch J, Guzman E, Audouard M, Bertucci T, Joy S, Rommelfanger E, Luna G, Keane-Rivera E, Lotz S, Borden S, Armando A, Quehenberger O, Temple S, Kosik K. Stem Cell Reports. PMID: 35985329. 2022.

Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration (PubMed)

Saini JS, Corneo B, Miller JD, Kiehl TR, Wang Q, Boles NC, Blenkinsop TA, Stern JH, Temple S. Cell Stem Cell. 2017 May 4;20(5):635-647.e7. doi: 10.1016/j.stem.2016.12.015. Epub 2017 Jan 26. PMID: 28132833; PMCID: PMC5419856.

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies (PubMed)

Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, Ghoshal N, Norton J, Huang Y, Lee SE, Seeley WW, Theofilas P, Grinberg LT, Moreno F, McIlroy K, Boeve BF, Cairns NJ, Crary JF, Haggarty SJ, Ichida JK, Kosik KS, Miller BL, Gan L, Goate AM, Temple S; Tau Consortium Stem Cell Group. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. 2019 Nov 12;13(5):939-955. doi: 10.1016/j.stemcr.2019.09.006. Epub 2019 Oct 17. PMID: 31631020; PMCID: PMC6895712.

The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue (PubMed)

Davis RJ, Alam NM, Zhao C, Müller C, Saini JS, Blenkinsop TA, Mazzoni F, Campbell M, Borden SM, Charniga CJ, Lederman PL, Aguilar V, Naimark M, Fiske M, Boles N, Temple S, Finnemann SC, Prusky GT, Stern JH. The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue. Stem Cell Reports. 2017 Jul 11;9(1):42-49. doi: 10.1016/j.stemcr.2017.05.016. Epub 2017 Jun 15. PMID: 28625537; PMCID: PMC5511099.