We harvest and expand neural stem cells and neural progenitor cells from mouse and human sources. Cells are frozen, thawed and performance tested before distribution.
Mouse Tissue and Cell Cultures: Our experienced technicians dissect mouse central nervous system (CNS) tissues at different stages of development, and provide either tissue or cell cultures from a variety of CNS regions, including cerebral cortex, striatum, cerebellum, hippocampus, choroid plexus, retina and spinal cord from embryonic day 11 through early postnatal stages. We can also supply adult mouse subventricular zone stem cell tissue and cultures.
Human iPSC and Neural Cell Products: We supply a variety of human iPSC lines, including unique genetically matched ocular iPSC lines from the retinal pigment epithelium and sclera or corneal-derived iPSCs from the same donors. Our specialty is differentiating iPSCs into nervous system products; we can provide, for example, human iPSC-derived neural progenitors, RPE, cerebral cortical cells and midbrain dopaminergic cells.
Human RPE: Our affiliates at the Neural Stem Cell Institute have created new ways to culture human RPE cells direct from cadaver eyes. We supply these human cobblestone polarized RPE cells, a valuable model of native RPE used to study health and disease states.